Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AQP1 | P29972 | 3/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 2/20 | 0.43 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.43 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.43 |
| ▸ | PRKAG3 | Q9UGI9 | 2/20 | 0.43 |
| ▸ | PRKAG2 | Q9UGJ0 | 2/20 | 0.43 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.43 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.40 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.39 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.32 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4229016 | 0.91 | AQP1 (0.58) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4221743 | 0.90 | AQP1 (0.46) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4232180 | 0.88 | AQP1 (0.54) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4219205 | 0.87 | AQP1 (0.53) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4225483 | 0.86 | AQP1 (0.53) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4226535 | 0.85 | PRKAB2 (0.43) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4226256 | 0.84 | PRKAB2 (0.45) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4230140 | 0.84 | AQP1 (0.45) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL27728293 | 0.83 | PRKAB2 (0.45) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL4230508 | 0.83 | AQP1 (0.61) | AQP1PRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101203216-A | Dihydrobenzofuran derivatives and uses thereof | WYETH CORP (US) | 2008-06-18 | — | — | CN | claimed |
| CN-101203216-A | Dihydrobenzofuran derivatives and uses thereof | WYETH CORP (US) | 2008-06-18 | — | — | CN | disclosed |