Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4A | O75164 | 4/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.43 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.43 |
| ▸ | KDM6B | O15054 | 2/20 | 0.43 |
| ▸ | KDM5C | P41229 | 2/20 | 0.43 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.41 |
| ▸ | FEN1 | P39748 | 2/20 | 0.41 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.39 |
| ▸ | USP19 | O94966 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27728466 | 0.85 | DRD2 (0.51) | KDM4AKDM4CKDM2AKDM6BKDM5C | |
| SCHEMBL28769966 | 0.82 | KDM2B (0.41) | KDM4AKDM4CKDM2AKDM6BKDM5C | |
| SCHEMBL27708035 | 0.82 | KDM2B (0.41) | KDM4AKDM4CKDM2AKDM6BKDM5C | |
| SCHEMBL28774040 | 0.82 | KDM2B (0.41) | KDM4AKDM4CKDM2AKDM6BKDM5C | |
| SCHEMBL27728545 | 0.81 | SCD (0.41) | KDM4AKDM4CKDM2AKDM6BKDM5C | |
| SCHEMBL27728464 | 0.78 | KDM2B (0.44) | KDM4AKDM4CKDM2AKDM6BKDM5C | |
| SCHEMBL410537 | 0.78 | MEN1 (0.47) | POLBALOX5APFEN1KMT2AMEN1 | |
| SCHEMBL27710693 | 0.78 | KDM4C (0.39) | KDM4AKDM4CKDM2AKDM6BKDM5C | |
| SCHEMBL27860541 | 0.78 | KDM4C (0.39) | KDM4AKDM4CKDM2AKDM6BKDM5C | |
| SCHEMBL27707947 | 0.78 | ATM (0.51) | KDM4AKDM4CKDM2AKDM6BKDM5C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228155-A | Substituted * oxadiazole derivatives as positive allosteric modulators of metabotropic glutamate receptors | ADDEX PHARMACEUTICALS SA (CH) | 2008-07-23 | — | — | CN | disclosed |