Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 1/20 | 0.41 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 6/20 | 0.39 |
| ▸ | KDM4A | O75164 | 5/20 | 0.39 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | KDM2A | Q9Y2K7 | 5/20 | 0.38 |
| ▸ | KDM6B | O15054 | 4/20 | 0.38 |
| ▸ | KDM5C | P41229 | 4/20 | 0.38 |
| ▸ | KDM3A | Q9Y4C1 | 3/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28769966 | 0.87 | KDM2B (0.41) | KDM2BKDM4CKDM4AGRM5KDM2A | |
| SCHEMBL27708035 | 0.87 | KDM2B (0.41) | KDM2BKDM4CKDM4AGRM5KDM2A | |
| SCHEMBL28774040 | 0.87 | KDM2B (0.41) | KDM2BKDM4CKDM4AGRM5KDM2A | |
| SCHEMBL27728466 | 0.81 | DRD2 (0.51) | KDM2BKDM4CKDM4AKDM2AKDM6B | |
| SCHEMBL27728541 | 0.81 | KDM4A (0.43) | KDM4CKDM4AKDM2AKDM6BKDM5C | |
| SCHEMBL27730855 | 0.80 | KDM2B (0.38) | KDM2BKDM4CKDM4AKDM2AKDM6B | |
| SCHEMBL27728464 | 0.79 | KDM2B (0.44) | KDM2BKDM4CKDM4AKDM2AKDM6B | |
| SCHEMBL27670316 | 0.79 | GRM5 (0.41) | KDM2BGRM5POLBNPC1 | |
| SCHEMBL27710693 | 0.79 | KDM4C (0.39) | KDM2BKDM4CKDM4AKDM2AKDM6B | |
| SCHEMBL27860541 | 0.79 | KDM4C (0.39) | KDM2BKDM4CKDM4AKDM2AKDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101228155-A | Substituted * oxadiazole derivatives as positive allosteric modulators of metabotropic glutamate receptors | ADDEX PHARMACEUTICALS SA (CH) | 2008-07-23 | — | — | CN | disclosed |