Pyridazine

Pyridazine

SCHEMBL27729005

O=[N+]([O-])c1ccc([N+](=O)[O-])cc1.c1ccnnc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.56
LMNA P02545 2/20 0.56
ACHE P22303 1/20 0.52
HSD17B10 Q99714 1/20 0.52
NPC1 O15118 1/20 0.50
MAPT P10636 1/20 0.50
RAB9A P51151 1/20 0.50
POLB P06746 1/20 0.50
L3MBTL1 Q9Y468 3/20 0.48
MEN1 O00255 1/20 0.48
CRHBP P24387 1/20 0.48
KMT2A Q03164 1/20 0.48
ATM Q13315 1/20 0.48
CRHR2 Q13324 1/20 0.48
TLR9 Q9NR96 1/20 0.48
HPGD P15428 1/20 0.48
ALOX12 P18054 1/20 0.48
CES1 P23141 2/20 0.48
TSHR P16473 1/20 0.48
CES2 O00748 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28311584 0.81 ALDH1A1 (0.82) ALDH1A1LMNAACHEHSD17B10POLB
SCHEMBL27909482 0.81 ALDH1A1 (0.72) ALDH1A1LMNAACHEHSD17B10MEN1
SCHEMBL22567 0.81 ALDH1A1 (0.72) ALDH1A1LMNAACHEHSD17B10MEN1
Pyrazine SCHEMBL27515795 0.79 MAPT (0.65) ALDH1A1LMNAACHEHSD17B10NPC1
Methyl Alcohol SCHEMBL27456236 0.78 HSD17B10 (0.70) ALDH1A1LMNAACHEHSD17B10MEN1
Hydrogen Sulfide SCHEMBL27319417 0.78 ALDH1A1 (0.68) ALDH1A1LMNAACHEHSD17B10MEN1
SCHEMBL27830410 0.78 ALDH1A1 (0.68) ALDH1A1LMNAACHEHSD17B10MEN1
Water SCHEMBL27300423 0.78 ALDH1A1 (0.68) ALDH1A1LMNAACHEHSD17B10MEN1
SCHEMBL27986433 0.78 ALDH1A1 (0.68) ALDH1A1LMNAACHEHSD17B10MEN1
SCHEMBL27844585 0.78 ALDH1A1 (0.68) ALDH1A1LMNAACHEHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101195672-B Method for producing olefin-copolymerization catalyst and method for producing olefin-copolymers SUMITOMO CHEMICAL CO 2011-07-06 CN disclosed
CN-101195672-A Method for producing olefin-copolymerization catalyst and method for producing olefin-copolymers SUMITOMO CHEMICAL CO (JP) 2008-06-11 CN disclosed