Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.38 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.38 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.38 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.38 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27749622 | 0.87 | FFAR1 (0.54) | FFAR1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL27729107 | 0.87 | RAB9A (0.38) | FFAR1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL2069424 | 0.82 | FFAR1 (0.42) | FFAR1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL30795492 | 0.82 | FFAR1 (0.42) | FFAR1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL27729309 | 0.81 | FFAR1 (0.66) | FFAR1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL27749765 | 0.76 | KDM4E (0.41) | FFAR1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL2069986 | 0.74 | KCNQ3 (0.47) | FFAR1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL30795429 | 0.74 | KCNQ3 (0.47) | FFAR1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL2070740 | 0.74 | SMN1; SMN2 (0.53) | FFAR1RAB9ASMN1; SMN2MAPTMEN1 | |
| SCHEMBL2070657 | 0.73 | FFAR1 (0.47) | FFAR1MAPTUTS2RF2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101378742-A | Use of KCNQ-openers for treating or alleviating the symptoms of schizophrenia | LUNDBECK & CO AS H (DK) | 2009-03-04 | — | — | CN | disclosed |