Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27729107 | 0.88 | RAB9A (0.38) | KDM4EGAAMAPTALDH1A1TDP1 | |
| SCHEMBL27749539 | 0.87 | GAA (0.51) | KDM4EGAAMAPTALDH1A1TDP1 | |
| SCHEMBL2069410 | 0.84 | KDR (0.46) | GAAMAPTALDH1A1RAB9AMEN1 | |
| SCHEMBL4975415 | 0.83 | MAPT (0.38) | KDM4EGAAMAPTALDH1A1POLB | |
| SCHEMBL27729021 | 0.82 | FFAR1 (0.45) | KDM4EGAAMAPTALDH1A1RAB9A | |
| SCHEMBL27729067 | 0.77 | KDM4C (0.50) | POLBMEN1KMT2A | |
| SCHEMBL27729239 | 0.76 | FFAR1 (0.52) | KDM4EGAAMAPTALDH1A1TDP1 | |
| SCHEMBL3099291 | 0.76 | KCNQ2 (0.62) | KDM4EMAPTALDH1A1TDP1RAB9A | |
| SCHEMBL30795564 | 0.76 | KCNQ3 (0.46) | MAPTALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL30795741 | 0.76 | KCNQ2 (0.62) | KDM4EMAPTALDH1A1TDP1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101378742-A | Use of KCNQ-openers for treating or alleviating the symptoms of schizophrenia | LUNDBECK & CO AS H (DK) | 2009-03-04 | — | — | CN | disclosed |