Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.40 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3106833 | 0.78 | RAB9A (0.44) | CSNK1DNAMPTKCNJ11NPC1RAB9A | |
| SCHEMBL30795357 | 0.78 | RAB9A (0.44) | CSNK1DNAMPTKCNJ11NPC1RAB9A | |
| SCHEMBL3609248 | 0.77 | KCNJ11 (0.46) | CSNK1DNAMPTKCNJ11NPC1RAB9A | |
| SCHEMBL28774176 | 0.75 | CSNK1D (0.43) | CSNK1DNAMPTKCNJ11NPC1RAB9A | |
| SCHEMBL3600618 | 0.73 | KCNJ11 (0.43) | CSNK1DNAMPTKCNJ11NPC1RAB9A | |
| SCHEMBL3101973 | 0.72 | CCR1 (0.45) | CSNK1DNAMPTKCNJ11NPC1RAB9A | |
| SCHEMBL19181787 | 0.71 | KCNJ11 (0.47) | CSNK1DNAMPTKCNJ11NPC1RAB9A | |
| SCHEMBL2438530 | 0.70 | L3MBTL1 (0.48) | NAMPTKCNJ11EPHX2LMNAMAPT | |
| SCHEMBL30795419 | 0.70 | L3MBTL1 (0.48) | NAMPTKCNJ11EPHX2LMNAMAPT | |
| SCHEMBL3104820 | 0.68 | RAB9A (0.50) | CSNK1DNAMPTKCNJ11NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101378742-A | Use of KCNQ-openers for treating or alleviating the symptoms of schizophrenia | LUNDBECK & CO AS H (DK) | 2009-03-04 | — | — | CN | disclosed |