Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B known ✓ | P18089 | 7/20 | 0.38 |
| ▸ | ADRA2C known ✓ | P18825 | 7/20 | 0.38 |
| ▸ | ADRA2A known ✓ | P08913 | 6/20 | 0.38 |
| ▸ | HTR1A known ✓ | P08908 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.41 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL730194 | 0.98 | ALDH1A1 (0.43) | ALDH1A1KDM4EMEN1GAAMAPT | |
| Formamide SCHEMBL27918478 | 0.89 | KDM4E (0.39) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL28191721 | 0.85 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL11214263 | 0.85 | ALDH1A1 (0.50) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL27895802 | 0.82 | ALDH1A1 (0.39) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL17968397 | 0.80 | MET (0.43) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL38230 | 0.80 | MET (0.40) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL1581213 | 0.79 | ALDH1A1 (0.44) | ALDH1A1KDM4EMEN1GAAMAPT | |
| SCHEMBL28133304 | 0.79 | CXCR4 (0.41) | ALDH1A1KDM4EMEN1GAAMAPT | |
| Hydrochloric Acid SCHEMBL28085302 | 0.79 | KDM4E (0.41) | ALDH1A1KDM4EMEN1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104350641-B | Additive for zinc-bromine without membrane flow battery | 溴化合物有限公司 | 2019-01-08 | — | — | CN | disclosed |
| CN-101218021-B | Use of a device for feeding at least one additive into the interior of a reactor | BASF AG | 2013-06-05 | — | — | CN | disclosed |
| CN-101218021-A | Use of a device for feeding at least one additive into the interior of a reactor | BASF AG (DE) | 2008-07-09 | — | — | CN | disclosed |