Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25218594 | 0.86 | NOTUM (0.50) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL4142743 | 0.85 | NOTUM (0.67) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL27729677 | 0.84 | NOTUM (0.67) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL6141916 | 0.84 | SMN1; SMN2 (0.66) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL10029580 | 0.82 | POLB (0.47) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL8577207 | 0.80 | NOTUM (0.70) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL3221069 | 0.79 | L3MBTL1 (0.48) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL18608896 | 0.78 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL20721701 | 0.78 | NOTUM (0.53) | MEN1KMT2ASMN1; SMN2MAPTNPC1 | |
| SCHEMBL10927840 | 0.77 | MAPT (0.44) | MEN1KMT2ASMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101209974-A | Hydroxamic acids derivatives and use thereof | TIANJIN INST PHARM RESEARCH (CN) | 2008-07-02 | — | — | CN | disclosed |