Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | CCR1 | P32246 | 2/20 | 0.43 |
| ▸ | MLNR | O43193 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.42 |
| ▸ | LIPC | P11150 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2776669 | 0.92 | SRD5A1 (0.45) | SRD5A1EPHX2NAMPTMLNRLMNA | |
| SCHEMBL2775803 | 0.85 | CCR1 (0.55) | SRD5A1EPHX2NAMPTCCR1LMNA | |
| SCHEMBL2780495 | 0.85 | CCR1 (0.55) | SRD5A1EPHX2NAMPTCCR1LMNA | |
| SCHEMBL6523989 | 0.85 | NAMPT (0.43) | SRD5A1EPHX2NAMPTCCR1LMNA | |
| SCHEMBL2776968 | 0.85 | NAMPT (0.48) | SRD5A1EPHX2NAMPTCCR1ADRB2 | |
| SCHEMBL2774857 | 0.82 | SRD5A1 (0.48) | SRD5A1EPHX2NAMPTMLNRLMNA | |
| SCHEMBL2779917 | 0.82 | NAMPT (0.47) | SRD5A1EPHX2NAMPTCCR1MLNR | |
| Hydrochloric Acid SCHEMBL2774192 | 0.80 | DPP4 (0.49) | SRD5A1EPHX2NAMPTMLNRMAPT | |
| SCHEMBL2774390 | 0.80 | POLB (0.55) | SRD5A1EPHX2NAMPTCCR1LMNA | |
| SCHEMBL2774417 | 0.80 | CCR1 (0.42) | SRD5A1EPHX2NAMPTCCR1MLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |