Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 3/20 | 0.40 |
| ▸ | LIPC | P11150 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2773036 | 0.85 | SRD5A1 (0.46) | NAMPTLMNAMAPTKMT2ASRD5A1 | |
| SCHEMBL2780495 | 0.84 | CCR1 (0.55) | NAMPTLMNAKMT2ASRD5A1CCR1 | |
| SCHEMBL2775803 | 0.84 | CCR1 (0.55) | NAMPTLMNAKMT2ASRD5A1CCR1 | |
| SCHEMBL2776968 | 0.83 | NAMPT (0.48) | NAMPTSRD5A1CCR1EPHX2HRH3 | |
| SCHEMBL2776669 | 0.82 | SRD5A1 (0.45) | NAMPTLMNAMAPTKMT2ASRD5A1 | |
| SCHEMBL2774857 | 0.79 | SRD5A1 (0.48) | NAMPTLMNAMAPTKMT2ASRD5A1 | |
| Hydrochloric Acid SCHEMBL2774192 | 0.79 | DPP4 (0.49) | NAMPTMAPTSRD5A1EPHX2HRH3 | |
| SCHEMBL2774390 | 0.79 | POLB (0.55) | NAMPTLMNASRD5A1CCR1EPHX2 | |
| SCHEMBL2779917 | 0.78 | NAMPT (0.47) | NAMPTSRD5A1CCR1EPHX2POLB | |
| SCHEMBL2776649 | 0.77 | EPHX2 (0.47) | NAMPTSRD5A1CCR1EPHX2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110053933-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2011-03-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053933-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | F12, F2, C3AR1 | NAMPT 1696/4885LMNA 1316/4885MAPT 4885/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.