Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.59 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.59 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | ACLY | P53396 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | PRNP | P04156 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3580345 | 0.98 | PTPN2 (0.61) | PTPN2PTPN1ABCC1KMT2AMEN1 | |
| SCHEMBL1317724 | 0.80 | PKM (0.53) | PTPN2PTPN1ABCC1KMT2AMEN1 | |
| SCHEMBL3706372 | 0.79 | PTPN2 (0.63) | PTPN2PTPN1ABCC1KMT2AMEN1 | |
| SCHEMBL18193263 | 0.78 | PTPN2 (0.41) | PTPN2PTPN1ABCC1KMT2AMEN1 | |
| SCHEMBL1704250 | 0.78 | PTPN2 (0.68) | PTPN2PTPN1ABCC1KMT2AMEN1 | |
| SCHEMBL3579523 | 0.78 | NPC1 (0.65) | KMT2AMEN1NPC1KDM4EALDH1A1 | |
| SCHEMBL23931980 | 0.78 | PTPN2 (0.72) | PTPN2PTPN1ABCC1KMT2AMEN1 | |
| SCHEMBL16396059 | 0.76 | ACLY (0.57) | PTPN2PTPN1ABCC1KMT2AMEN1 | |
| SCHEMBL1285826 | 0.75 | PTPN2 (0.58) | PTPN2PTPN1ABCC1KMT2AMEN1 | |
| SCHEMBL16413175 | 0.74 | PTPN2 (0.58) | PTPN2PTPN1ABCC1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101379036-B | Anthranilamide/2-amino-heteroarene carboxamide derivatives | HOFFMANN LA ROCHE | 2011-06-01 | — | — | CN | disclosed |
| CN-101379036-A | Anthranilamide/2-amino-heteroarene carboxamide derivatives | HOFFMANN LA ROCHE (CH) | 2009-03-04 | — | — | CN | disclosed |