Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 6/20 | 0.61 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | QDPR | P09417 | 1/20 | 0.41 |
| ▸ | ELANE | P08246 | 5/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27616089 | 0.86 | DRD2 (0.48) | HTR2C | |
| SCHEMBL27741863 | 0.83 | HTR2C (0.57) | HTR2CSLC18A3SIGMAR1QDPR | |
| SCHEMBL27674642 | 0.83 | ELANE (0.53) | HTR2CSLC18A3SIGMAR1ELANE | |
| SCHEMBL28082233 | 0.82 | HTR2C (0.61) | HTR2CSLC18A3SIGMAR1QDPRPARP1 | |
| SCHEMBL16829577 | 0.81 | HTR2C (0.61) | HTR2C | |
| SCHEMBL28871195 | 0.81 | HRH1 (0.50) | ELANEHTR6 | |
| Hydrochloric Acid SCHEMBL16829616 | 0.80 | HTR2C (0.62) | HTR2C | |
| SCHEMBL14999424 | 0.79 | HTR2C (0.69) | HTR2CSLC18A3SIGMAR1QDPR | |
| SCHEMBL16829583 | 0.78 | HTR2C (0.57) | HTR2C | |
| SCHEMBL4765094 | 0.78 | ACHE (0.60) | HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829297-B | Piperidine compounds having multimodal activity against pain | 埃斯蒂文制药股份有限公司 | 2019-08-09 | — | — | CN | disclosed |
| CN-105829297-A | PIPERIDINE COMPOUNDS HAVING MULTIMODAL ACTIVITY AGAINST PAIN | 埃斯蒂文博士实验室股份有限公司 | 2016-08-03 | — | — | CN | disclosed |
| CN-102203074-A | Aryl GPR119 agonists and uses thereof | METABOLEX INC | 2011-09-28 | — | — | CN | disclosed |
| CN-101370812-A | Fused heterocyclic compound | TAKEDA PHARMACEUTICAL (JP) | 2009-02-18 | — | — | CN | disclosed |