Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CDK4 | P11802 | 5/20 | 0.43 |
| ▸ | CCND1 | P24385 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | CDK2 | P24941 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL322185 | 0.82 | NPC1 (0.46) | CYP1A2CYP2D6CYP2C9CYP2C19KMT2A | |
| SCHEMBL16333188 | 0.81 | HTR1A (0.54) | TAAR1CDK4CCND1CDK2KMT2A | |
| SCHEMBL555604 | 0.79 | TAAR1 (0.62) | TAAR1CDK4CCND1KMT2ANPC1 | |
| SCHEMBL18422574 | 0.79 | TAAR1 (0.62) | TAAR1CDK4CCND1KMT2ANPC1 | |
| SCHEMBL27759121 | 0.79 | SIGMAR1 (0.47) | CDK4CCND1CDK2KMT2ANPC1 | |
| SCHEMBL1690653 | 0.79 | MEN1 (0.44) | TAAR1CDK4CCND1CYP1A2CYP2D6 | |
| SCHEMBL3056915 | 0.77 | TAAR1 (0.59) | TAAR1SIGMAR1HTR1AHTR1BHTR2A | |
| SCHEMBL23925502 | 0.77 | AOC3 (0.61) | TAAR1CDK4CCND1KMT2AKDM4E | |
| SCHEMBL8751582 | 0.77 | HCRTR1 (0.54) | CYP1A2CYP2D6CYP2C19KMT2AKDM4E | |
| SCHEMBL1520363 | 0.76 | KMT2A (0.59) | TAAR1KMT2ANPC1RAB9ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101238101-A | 2-(1H-indolylsulfanyl)-aryl amine derivatives | LUNDBECK & CO AS H (DK) | 2008-08-06 | — | — | CN | disclosed |