Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.65 |
| ▸ | MEN1 | O00255 | 8/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.65 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.65 |
| ▸ | RAB9A | P51151 | 10/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | NPC1 | O15118 | 7/20 | 0.58 |
| ▸ | CASP3 | P42574 | 2/20 | 0.58 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.58 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.58 |
| ▸ | SENP6 | Q9GZR1 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18985301 | 0.83 | RAB9A (0.74) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL18985299 | 0.83 | RAB9A (0.74) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL27752045 | 0.82 | RAB9A (0.67) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL3040770 | 0.82 | RAB9A (0.69) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL27752058 | 0.82 | RAB9A (0.67) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL3040771 | 0.82 | RAB9A (0.69) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL27752021 | 0.82 | RAB9A (0.67) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL17664304 | 0.82 | MAPT (0.48) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL28774771 | 0.78 | MAPT (0.72) | MAPTMEN1KMT2AMAPK1LMNA | |
| SCHEMBL27752020 | 0.78 | MAPT (0.67) | MAPTMEN1KMT2AMAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101365681-B | Iminopropene compound and use thereof | SUMITOMO CHEMICAL CO | 2013-01-02 | — | — | CN | disclosed |
| CN-101365681-A | Iminopropene compound and use thereof | SUMITOMO CHEMICAL CO (JP) | 2009-02-11 | — | — | CN | disclosed |