Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.91 |
| ▸ | HTR2C | P28335 | 1/20 | 0.91 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.91 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | HTR6 | P50406 | 4/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.51 |
| ▸ | NCF1 | P14598 | 2/20 | 0.51 |
| ▸ | HTR5A | P47898 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.51 |
| ▸ | HTR3B | O95264 | 2/20 | 0.51 |
| ▸ | HTR3A | P46098 | 2/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | HTR1D | P28221 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1045944 | 0.95 | HTR2A (1.00) | HTR2AHTR2CSLC6A4HTR7HTR6 | |
| Hydrochloric Acid SCHEMBL1048620 | 0.94 | HTR2A (0.97) | HTR2AHTR2CSLC6A4HTR7HTR6 | |
| SCHEMBL7515421 | 0.90 | HTR2A (0.88) | HTR2AHTR2CSLC6A4HTR7HTR6 | |
| SCHEMBL29746904 | 0.80 | HTR2A (0.73) | HTR2AHTR2CSLC6A4HTR7HTR6 | |
| SCHEMBL8961462 | 0.80 | HTR2A (0.73) | HTR2AHTR2CSLC6A4HTR7HTR6 | |
| SCHEMBL4884479 | 0.79 | HTR2A (0.67) | HTR2AHTR2CSLC6A4HTR7HTR6 | |
| SCHEMBL4143098 | 0.79 | HTR2A (0.67) | HTR2AHTR2CSLC6A4HTR7HTR6 | |
| SCHEMBL9673340 | 0.79 | HTR2A (0.71) | HTR2AHTR2CSLC6A4HTR7HTR6 | |
| SCHEMBL6639825 | 0.79 | HTR2A (0.70) | HTR2AHTR2CSLC6A4HTR7HTR6 | |
| SCHEMBL23602033 | 0.78 | HTR2A (0.65) | HTR2AHTR2CSLC6A4HTR1ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101243073-A | Piperazine-piperidine antagonists and agonists of the 5-HT1A receptor | WYETH CORP (US) | 2008-08-13 | — | — | CN | disclosed |