Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.73 |
| ▸ | HTR2C | P28335 | 1/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.73 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.52 |
| ▸ | HRH1 | P35367 | 3/20 | 0.52 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.50 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.50 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29746904 | 1.00 | HTR2A (0.73) | HTR2AHTR2CSLC6A4ADRA1AHRH1 | |
| SCHEMBL9673340 | 0.98 | HTR2A (0.71) | HTR2AHTR2CSLC6A4ADRA1AHRH1 | |
| SCHEMBL12932459 | 0.86 | HTR2A (0.60) | HTR2AHTR2CSLC6A4ADRA1AHRH1 | |
| SCHEMBL7515421 | 0.86 | HTR2A (0.88) | HTR2AHTR2CSLC6A4MAPTHTR1A | |
| SCHEMBL13772684 | 0.84 | HTR2A (0.67) | HTR2AHTR2CSLC6A4ADRA1AHRH1 | |
| SCHEMBL1045944 | 0.84 | HTR2A (1.00) | HTR2AHTR2CSLC6A4MAPTHTR1A | |
| Hydrochloric Acid SCHEMBL1048620 | 0.83 | HTR2A (0.97) | HTR2AHTR2CSLC6A4MAPTHTR1A | |
| SCHEMBL3565769 | 0.83 | HTR2A (0.65) | HTR2AHTR2CSLC6A4HTR1AALDH1A1 | |
| SCHEMBL30600597 | 0.82 | HTR2A (0.63) | HTR2AHTR2CSLC6A4ADRA1AHRH1 | |
| Methyl Alcohol SCHEMBL27731985 | 0.80 | HTR2A (0.91) | HTR2AHTR2CSLC6A4MAPTHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656389-B | Synthesis method of 1-phenylpyrrolidine | 河南大学 | 2023-12-15 | — | — | CN | disclosed |
| CN-114656389-A | Synthesis method of 1-phenylpyrrolidine | 河南大学 | 2022-06-24 | — | — | CN | disclosed |
| EP-0534844-B1 | New derivatives of decahydroquinoline, process for their preparation, intermediaires of the preparation, their use as medicines and compositions containing them | ROUSSEL UCLAF (FR) | 1996-02-07 | — | — | EP | disclosed |
| EP-0534844-A1 | New derivatives of decahydroquinoline, process for their preparation, intermediaires of the preparation, their use as medicines and compositions containing them | ROUSSEL UCLAF (FR) | 1993-03-31 | — | — | EP | disclosed |
| EP-0233793-B1 | DECAHYDROQUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, INTERMEDIATES FOR THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1992-04-01 | — | — | EP | disclosed |
| EP-0233793-A2 | Decahydroquinoline derivatives, process for their preparation, intermediates for their preparation, their use as medicaments and compositions containing them | ROUSSEL-UCLAF (FR) | 1987-08-26 | — | — | EP | disclosed |