Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.53 |
| ▸ | MLNR | O43193 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.44 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6443537 | 0.81 | MLNR (0.55) | EPHX2MLNRADRB2KMT2AMEN1 | |
| SCHEMBL27900122 | 0.81 | ADRB2 (0.53) | EPHX2MLNRADRB2PLA2G1BATG4B | |
| Hydrochloric Acid SCHEMBL27826424 | 0.80 | MLNR (0.52) | EPHX2MLNRADRB2KMT2AMEN1 | |
| SCHEMBL4578888 | 0.79 | ADRB2 (0.52) | EPHX2MLNRADRB2PLA2G1BATG4B | |
| SCHEMBL14412954 | 0.78 | EPHX2 (0.62) | EPHX2MLNRADRB2KMT2AMEN1 | |
| SCHEMBL2776649 | 0.78 | EPHX2 (0.47) | EPHX2MLNRADRB2POLBL3MBTL1 | |
| SCHEMBL2774350 | 0.78 | SCD (0.46) | EPHX2MLNRSCD | |
| SCHEMBL5210775 | 0.77 | EPHX2 (0.51) | EPHX2MLNRADRB2PLA2G1BATG4B | |
| SCHEMBL7092551 | 0.76 | EPHX2 (0.57) | EPHX2KMT2AMEN1 | |
| SCHEMBL14412779 | 0.76 | EPHX2 (0.57) | EPHX2MLNRADRB2PLA2G1BATG4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2258697-A1 | HYDROXYQUINOXALINECARBOXAMIDE DERIVATIVE | Daiichi Sankyo Company, Limited (JP) | 2010-12-08 | — | — | EP | disclosed |