Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1781579 | 0.86 | KDM4E (0.56) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL12608099 | 0.79 | KDM4E (0.48) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL27732798 | 0.78 | GAA (0.35) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL1445236 | 0.78 | KDM4E (0.47) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL1445183 | 0.78 | MIF (0.52) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL4828368 | 0.78 | KDM4E (0.47) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL27732880 | 0.76 | ASIC3 (0.55) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL13966932 | 0.75 | KDM4E (0.42) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL28634084 | 0.74 | MEN1 (0.62) | MEN1KMT2AMAPTSMN1; SMN2GAA | |
| SCHEMBL25547161 | 0.74 | NPC1 (0.61) | MEN1KMT2AMAPTSMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101257948-A | Pyrimidine-fused diazepine derivatives and indole-fused pteridines | ATTENUON LLC (US) | 2008-09-03 | — | — | CN | disclosed |