Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CTSL | P07711 | 5/20 | 0.48 |
| ▸ | CTSB | P07858 | 5/20 | 0.48 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8240099 | 1.00 | HTT (0.56) | HTTSMN1; SMN2L3MBTL1ATMKMT2A | |
| SCHEMBL13619512 | 1.00 | HTT (0.56) | HTTSMN1; SMN2L3MBTL1ATMKMT2A | |
| SCHEMBL7365207 | 0.87 | ALDH1A1 (0.57) | SMN1; SMN2ATMKMT2ACYP3A4TSHR | |
| SCHEMBL11533827 | 0.86 | SMN1; SMN2 (0.56) | HTTSMN1; SMN2L3MBTL1ATMKMT2A | |
| SCHEMBL3863271 | 0.84 | HTT (0.54) | HTTSMN1; SMN2L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL3863275 | 0.84 | HTT (0.54) | HTTSMN1; SMN2L3MBTL1RAB9AALDH1A1 | |
| SCHEMBL6648096 | 0.84 | L3MBTL1 (0.51) | HTTSMN1; SMN2L3MBTL1RAB9APDE1C | |
| SCHEMBL2191058 | 0.83 | L3MBTL1 (0.54) | HTTSMN1; SMN2L3MBTL1ATMKMT2A | |
| SCHEMBL30460502 | 0.82 | ATM (0.68) | ATMKMT2ACYP3A4TSHRMEN1 | |
| SCHEMBL21469067 | 0.82 | ATM (0.68) | ATMKMT2ACYP3A4TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110669015-A | Preparation method of FGFR inhibitor | 上海喀露蓝科技有限公司 | 2020-01-10 | — | — | CN | disclosed |
| CN-101389613-B | Macrocyclic factor viia inhibitors useful as anticoagulants | BRISTOL MYERS SQUIBB CO | 2011-10-12 | — | — | CN | disclosed |
| CN-101389613-A | Macrocyclic factor viia inhibitors useful as anticoagulants | BRISTOL MYERS SQUIBB CO (US) | 2009-03-18 | — | — | CN | disclosed |