Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.53 |
| ▸ | CRHBP | P24387 | 1/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | FNTA | P49354 | 5/20 | 0.52 |
| ▸ | FNTB | P49356 | 5/20 | 0.52 |
| ▸ | KLK7 | P49862 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733288 | 0.93 | FNTA (0.57) | KMT2AMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL27818037 | 0.92 | FNTA (0.56) | KMT2AMEN1LMNANPSR1FNTA | |
| SCHEMBL27733287 | 0.85 | FNTA (0.51) | KMT2AMEN1LMNAFNTAFNTB | |
| SCHEMBL27818040 | 0.83 | MEN1 (0.56) | KMT2AMEN1LMNAHTTKLK7 | |
| SCHEMBL27713011 | 0.83 | MEN1 (0.57) | KMT2AMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL10954976 | 0.81 | LMNA (0.68) | KMT2AMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL27712950 | 0.81 | KMT2A (0.50) | KMT2AMEN1LMNAHTTNPSR1 | |
| SCHEMBL13674804 | 0.78 | DCAF1 (0.51) | KMT2AMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL24968752 | 0.76 | KMT2A (0.51) | KMT2AMEN1LMNACYP1A2CYP3A4 | |
| SCHEMBL10952833 | 0.73 | HTT (0.58) | KMT2AMEN1LMNACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101250134-B | N-aryl-beta-aryl amidine-propionamide compounds, preparation method and use thereof | UNIV SICHUAN | 2011-07-20 | — | — | CN | claimed |
| CN-101250134-A | N-aryl-beta-aryl amidine-propionamide compounds, preparation method and use thereof | UNIV SICHUAN (CN) | 2008-08-27 | — | — | CN | claimed |