Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCAF1 | Q9Y4B6 | 5/20 | 0.51 |
| ▸ | KLK7 | P49862 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8996250 | 0.84 | EEF2K (0.51) | FNTAFNTBNPC1RAB9A | |
| SCHEMBL8996304 | 0.84 | EEF2K (0.51) | FNTAFNTBNPC1RAB9A | |
| SCHEMBL29157134 | 0.79 | CTSA (0.49) | MEN1KMT2ACYP2C19LMNACYP1A2 | |
| SCHEMBL27733289 | 0.78 | KMT2A (0.53) | KLK7MEN1KMT2ACYP2C19LMNA | |
| SCHEMBL9298256 | 0.75 | EEF2K (0.48) | CYP2C19LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5691034 | 0.75 | EEF2K (0.48) | CYP2C19LMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14223257 | 0.74 | FPR2 (0.47) | MEN1KMT2ACYP2C19CYP1A2CYP3A4 | |
| SCHEMBL9169362 | 0.74 | ALDH1A1 (0.47) | ALDH1A1 | |
| SCHEMBL17375914 | 0.74 | DCAF1 (0.53) | DCAF1KMT2ACYP2C19LMNACYP1A2 | |
| SCHEMBL16348724 | 0.74 | ALDH1A1 (0.56) | DCAF1CYP2C19LMNACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7601842-B2 | Method for producing an optically active tetrahydroquinoline | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2009-10-13 | — | — | US | disclosed |