Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD11B2 | P80365 | 1/20 | 0.32 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cicrotoic Acid SCHEMBL2773332 | 1.00 | CES2 (0.44) | CES2CES1HDAC8HDAC6TSHR | |
| Cicrotoic Acid SCHEMBL1642993 | 1.00 | CES2 (0.44) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL13468227 | 0.98 | CES2 (0.40) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL13468214 | 0.93 | CES2 (0.35) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL3139362 | 0.88 | — | — | |
| SCHEMBL12491769 | 0.88 | — | — | |
| SCHEMBL3139365 | 0.88 | — | — | |
| SCHEMBL9609535 | 0.84 | CES2 (0.46) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL11871555 | 0.82 | CES2 (0.44) | CES2CES1HDAC8HDAC6TSHR | |
| SCHEMBL11871558 | 0.82 | CES2 (0.44) | CES2CES1HDAC8HDAC6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055254-A2 | FORMULATIONS AND METHODS FOR ORAL DELIVERY OF PROTEINS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2008-05-08 | — | — | WO | claimed |
| CN-116854744-A | Synthesis and application of chiral spiro [ chromane-4, 1' -indan ] bidentate ligand iridium complex | 南开大学 | 2023-10-10 | — | — | CN | disclosed |
| CN-114174584-A | Fabric spray composition | 联合利华知识产权控股有限公司 | 2022-03-11 | — | — | CN | disclosed |
| US-10835609-B2 | Hydrogels for delivery of therapeutic compounds | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2020-11-17 | — | — | US | disclosed |
| US-10500256-B2 | Polymers for delivery of therapeutic proteins | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-12-10 | — | — | US | disclosed |
| US-20190275162-A1 | POLYMERS FOR DELIVERY OF FACTOR VIII AND/OR FACTOR IX | UNIV TEXAS (US) | 2019-09-12 | — | — | US | disclosed |
| US-10265405-B2 | Polymers for delivery of factor VIII and/or factor IX | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2019-04-23 | — | — | US | disclosed |
| US-20180256724-A1 | HYDROGELS FOR DELIVERY OF THERAPEUTIC COMPOUNDS | UNIV TEXAS (US) | 2018-09-13 | — | — | US | disclosed |
| US-9937256-B2 | Hydrogels for delivery of therapeutic compounds | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-04-10 | — | — | US | disclosed |
| US-20160206741-A1 | HYDROGELS FOR DELIVERY OF THERAPEUTIC COMPOUNDS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2016-07-21 | — | — | US | disclosed |
| EP-0372709-A1 | Improved dispersant additives prepared from monoepoxy alcohols | EXXON CHEMICAL PATENTS INC. (US) | 1990-06-13 | — | — | EP | disclosed |
| EP-0369641-A1 | Improved dispersant additives prepared from monoepoxy thiols | EXXON CHEMICAL PATENTS INC. (US) | 1990-05-23 | — | — | EP | disclosed |
| EP-0368548-A1 | Improved amide dispersant additives derived from amido-amines | EXXON CHEMICAL PATENTS INC. (US) | 1990-05-16 | — | — | EP | disclosed |
| WO-1990004625-A2 | AMIDE CONTAINING FRICTION MODIFIER FOR USE IN POWER TRANSMISSION FLUIDS | EXXON CHEMICAL COMPANY (US) | 1990-05-03 | — | — | WO | disclosed |
| EP-0357217-A2 | Ethylene alpha-olefin copolymer substituted amino phenol mannich base lubricant dispersant additives | EXXON CHEMICAL PATENTS INC. (US) | 1990-03-07 | — | — | EP | disclosed |
| EP-0356010-A1 | Ethylene alpha-olefin polymer substituted Mannich base lubricant dispersant additives | EXXON CHEMICAL PATENTS INC. (US) | 1990-02-28 | — | — | EP | disclosed |
| EP-0353935-A1 | Ethylene alpha-olefin polymer substituted mono-and dicarboxylic acid lubricant dispersant additives | EXXON CHEMICAL PATENTS INC. (US) | 1990-02-07 | — | — | EP | disclosed |
| EP-0336664-A2 | Improved dispersant additives derived from amido-amine adducts | EXXON CHEMICAL PATENTS INC. (US) | 1989-10-11 | — | — | EP | disclosed |
| US-4857217-A | ADDUCT OF POLYOLEFIN MODIFIED WITH AN ACID AND POLYAMINE MODIFIED WITH (THIO)AMIDO COMPOUND | EXXON CHEMICAL PATENTS INC. (US) | 1989-08-15 | — | — | US | disclosed |
| EP-0319229-A2 | Improved dispersant additives derived from amido-amines | EXXON CHEMICAL PATENTS INC. (US) | 1989-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190275162-A1 | POLYMERS FOR DELIVERY OF FACTOR VIII AND/OR FACTOR IX | F8, F9, F13A1 | CES2 2821/4885CES1 3978/4885HDAC8 667/4885 |
| US-10265405-B2 | Polymers for delivery of factor VIII and/or factor IX | F8, F9, F13A1 | CES2 2821/4885CES1 3978/4885HDAC8 667/4885 |
| US-10835609-B2 | Hydrogels for delivery of therapeutic compounds | SI, VIP, DNPEP | CES2 542/4885CES1 737/4885HDAC8 551/4885 |
| US-20180256724-A1 | HYDROGELS FOR DELIVERY OF THERAPEUTIC COMPOUNDS | SI, VIP, DNPEP | CES2 542/4885CES1 737/4885HDAC8 551/4885 |
| US-20160206741-A1 | HYDROGELS FOR DELIVERY OF THERAPEUTIC COMPOUNDS | SI, VIP, DNPEP | CES2 542/4885CES1 737/4885HDAC8 551/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.