Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129443 | 0.87 | SMN1; SMN2 (0.53) | SMN1; SMN2ALDH1A1TP53MAPTHPGD | |
| SCHEMBL12926334 | 0.87 | MEN1 (0.50) | SMN1; SMN2ALDH1A1TP53MAPTHPGD | |
| SCHEMBL4867973 | 0.85 | MAOB (0.49) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL3589633 | 0.83 | NQO1 (0.50) | MAPTTSHRAPPNQO1MMP2 | |
| SCHEMBL6125304 | 0.82 | MEN1 (0.46) | SMN1; SMN2ALDH1A1TP53MAPTHPGD | |
| SCHEMBL11110682 | 0.80 | CYP3A4 (0.62) | SMN1; SMN2ALDH1A1TP53MAPTTSHR | |
| SCHEMBL12926333 | 0.80 | SMN1; SMN2 (0.36) | SMN1; SMN2ALDH1A1TP53MAPTHPGD | |
| SCHEMBL25124165 | 0.79 | ESR1 (0.57) | SMN1; SMN2ALDH1A1TP53MAPTHPGD | |
| SCHEMBL14369400 | 0.78 | KDM4E (0.48) | SMN1; SMN2ALDH1A1MEN1KMT2ACYP3A4 | |
| SCHEMBL23803508 | 0.78 | MMP2 (0.34) | SMN1; SMN2ALDH1A1TP53MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101180097-A | Novel phosphinic acid-containing thyromimetics | METABASIS THERAPEUTICS INC (US) | 2008-05-14 | — | — | CN | disclosed |