Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 5/20 | 0.47 |
| ▸ | NR1H2 | P55055 | 4/20 | 0.47 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | RORC | P51449 | 4/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | RORA | P35398 | 1/20 | 0.33 |
| ▸ | RORB | Q92753 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6917666 | 0.74 | NR1H3 (0.69) | NR1H3NR1H2APOBEC3GRORCNR1I2 | |
| SCHEMBL2512045 | 0.68 | APOBEC3G (0.58) | NR1H3NR1H2APOBEC3GHTR6TDP1 | |
| SCHEMBL10873132 | 0.68 | NR1H3 (0.55) | NR1H3NR1H2 | |
| SCHEMBL3398530 | 0.67 | NR1H2 (0.55) | NR1H3NR1H2APOBEC3GRORCNR1I2 | |
| SCHEMBL8740801 | 0.66 | NR1H2 (0.41) | NR1H3NR1H2 | |
| SCHEMBL7211483 | 0.66 | PKM (0.58) | NR1H3NR1H2APOBEC3GRORCNR1I2 | |
| SCHEMBL28793753 | 0.66 | NR1H3 (0.54) | NR1H3NR1H2APOBEC3GRORCNR1I2 | |
| SCHEMBL1868116 | 0.65 | APOBEC3G (0.54) | NR1H3NR1H2APOBEC3GHTR6TDP1 | |
| SCHEMBL1768495 | 0.65 | APOBEC3G (0.54) | NR1H3NR1H2APOBEC3GRORCNR1I2 | |
| SCHEMBL11406942 | 0.65 | NR1H3 (0.56) | NR1H3NR1H2APOBEC3GRORCNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |