Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SLC40A1 | Q9NP59 | 3/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 3/20 | 0.33 |
| ▸ | PPARA | Q07869 | 3/20 | 0.33 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28770822 | 0.89 | RAB9A (0.37) | NTSR1KMT2AMEN1HSP90AA1POLB | |
| SCHEMBL27713371 | 0.85 | PPARG (0.42) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL27733855 | 0.84 | RECQL (0.41) | KMT2AMEN1RECQLPPARGPPARA | |
| SCHEMBL28775103 | 0.81 | MEN1 (0.41) | KMT2AMEN1PSEN1PSEN2APH1B | |
| SCHEMBL27733786 | 0.81 | PPARG (0.39) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL27733784 | 0.80 | PSEN1 (0.42) | KMT2AMEN1PSEN1PSEN2APH1B | |
| SCHEMBL27713457 | 0.79 | PSEN1 (0.46) | KMT2AMEN1PSEN1PSEN2APH1B | |
| SCHEMBL27713686 | 0.79 | PPARG (0.41) | KMT2AMEN1PSEN1PSEN2APH1B | |
| SCHEMBL28770843 | 0.78 | PPARG (0.34) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL27713338 | 0.77 | PSEN1 (0.40) | KMT2AMEN1PSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |