Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 7/20 | 0.35 |
| ▸ | PPARA | Q07869 | 6/20 | 0.35 |
| ▸ | PPARD | Q03181 | 4/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27733728 | 0.89 | NTSR1 (0.36) | RAB9AHSP90AA1PPARGPPARAPPARD | |
| SCHEMBL27733726 | 0.86 | PPARG (0.42) | PPARGPPARAPPARDKMT2AMEN1 | |
| SCHEMBL28775109 | 0.84 | RECQL (0.39) | PPARGPPARAPPARDKMT2AMEN1 | |
| SCHEMBL27733882 | 0.81 | PPARG (0.38) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL27833766 | 0.80 | PHGDH (0.38) | PPARGPPARAPPARDKMT2AMEN1 | |
| SCHEMBL27733711 | 0.80 | PPARG (0.41) | PPARGPPARAPPARDKMT2AMEN1 | |
| SCHEMBL27733852 | 0.80 | PSEN1 (0.39) | PPARGPPARAPPARDPOLB | |
| SCHEMBL27733674 | 0.76 | CYP3A4 (0.34) | PPARGPPARAPPARDKDM4E | |
| SCHEMBL27733841 | 0.76 | F7 (0.36) | PPARGPPARAPPARD | |
| SCHEMBL27733702 | 0.75 | PPARG (0.46) | RAB9APPARGPPARAPPARDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |