Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 2/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28705560 | 0.83 | CTSK (0.39) | CTSKCA1CA2CA7NOS1 | |
| SCHEMBL17871166 | 0.82 | CTSK (0.38) | CTSKCA1CA2CA7NOS1 | |
| SCHEMBL4901433 | 0.80 | CTSK (0.33) | CTSKCA1CA2CA7NOS1 | |
| SCHEMBL9954495 | 0.80 | TSHR (0.35) | CTSKCA1CA2CA7NOS1 | |
| SCHEMBL7324930 | 0.80 | CTSK (0.33) | CTSKCA1CA2CA7NOS1 | |
| SCHEMBL16574707 | 0.80 | TSHR (0.35) | CTSKCA1CA2CA7NOS1 | |
| SCHEMBL28950491 | 0.77 | CTSK (0.35) | CTSKCA1CA2CA7NOS1 | |
| SCHEMBL28705561 | 0.77 | CTSK (0.35) | CTSKCA1CA2CA7NOS1 | |
| SCHEMBL14593924 | 0.76 | CA1 (0.38) | CTSKCA1CA2CA7NOS1 | |
| SCHEMBL21130051 | 0.75 | ALDH1A1 (0.39) | LMNACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189222-A | Tri-, tetra-substituted-3-aminopyrrolidine derivative | DAIICHI SEIYAKU CO (JP) | 2008-05-28 | — | — | CN | disclosed |