Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.32 |
| ▸ | CTSL | P07711 | 1/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.32 |
| ▸ | YAP1 | P46937 | 1/20 | 0.32 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713389 | 1.00 | ALDH1A1 (0.37) | ALDH1A1JAK2JAK1STSKMT2A | |
| SCHEMBL27733729 | 0.88 | ALDH1A1 (0.40) | ALDH1A1JAK2JAK1KMT2AL3MBTL1 | |
| SCHEMBL27713416 | 0.88 | ALDH1A1 (0.40) | ALDH1A1JAK2JAK1KMT2AL3MBTL1 | |
| SCHEMBL27733741 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KMT2APOLBCYP3A4CYP2C9 | |
| SCHEMBL27713377 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KMT2APOLBCYP3A4CYP2C9 | |
| SCHEMBL27733866 | 0.83 | KMT2A (0.38) | ALDH1A1KMT2AL3MBTL1CTSLCTSS | |
| SCHEMBL28770888 | 0.83 | KMT2A (0.38) | ALDH1A1KMT2AL3MBTL1CTSLCTSS | |
| SCHEMBL28775111 | 0.76 | ALDH1A1 (0.46) | ALDH1A1POLBCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL27733746 | 0.67 | SMN1; SMN2 (0.44) | KMT2AAGTR2CYP2C19RORC | |
| SCHEMBL27733865 | 0.67 | SMN1; SMN2 (0.44) | KMT2AAGTR2CYP2C19RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101189222-B | Tri-, tetra-substituted-3-aminopyrrolidine derivative | DAIICHI SANKYO CO LTD | 2013-01-02 | — | — | CN | disclosed |
| CN-101189222-A | Tri-, tetra-substituted-3-aminopyrrolidine derivative | DAIICHI SEIYAKU CO (JP) | 2008-05-28 | — | — | CN | disclosed |