Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 8/20 | 0.42 |
| ▸ | WNT3 | P56703 | 2/20 | 0.42 |
| ▸ | HTR6 | P50406 | 7/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tert-Butyl Formate SCHEMBL28775035 | 0.90 | SFRP1 (0.48) | SFRP1WNT3HTR6HTR2CHTR2B | |
| Acetic Acid SCHEMBL27713022 | 0.88 | SFRP1 (0.46) | SFRP1WNT3HTR6HTR2CHTR2B | |
| Tert-Butyl Formate SCHEMBL27733330 | 0.82 | SFRP1 (0.48) | SFRP1WNT3HTR6 | |
| Tert-Butyl Formate SCHEMBL28770795 | 0.81 | SFRP1 (0.45) | SFRP1WNT3HTR6BRD4BRD2 | |
| Tert-Butyl Formate SCHEMBL27712971 | 0.80 | SFRP1 (0.44) | SFRP1WNT3HTR6BRD4BRD2 | |
| Tert-Butyl Formate SCHEMBL27712926 | 0.80 | SFRP1 (0.48) | SFRP1WNT3HTR6 | |
| Tert-Butyl Formate SCHEMBL27713092 | 0.79 | SFRP1 (0.58) | SFRP1WNT3 | |
| SCHEMBL27713263 | 0.77 | SFRP1 (0.45) | SFRP1WNT3 | |
| Fluorobenzene SCHEMBL27733569 | 0.74 | SFRP1 (0.44) | SFRP1WNT3 | |
| Tert-Butyl Formate SCHEMBL27733745 | 0.71 | SFRP1 (0.65) | SFRP1WNT3BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | claimed |
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |