Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SFRP1 | Q8N474 | 19/20 | 0.65 |
| ▸ | WNT3 | P56703 | 6/20 | 0.65 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | BRD2 | P25440 | 1/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616681 | 0.91 | SFRP1 (0.70) | SFRP1WNT3BRD4BRD2BRD3 | |
| SCHEMBL4619410 | 0.82 | SFRP1 (0.57) | SFRP1WNT3BRD4BRD2BRD3 | |
| Tert-Butyl Formate SCHEMBL28775035 | 0.82 | SFRP1 (0.48) | SFRP1WNT3BRD4BRD2BRD3 | |
| SCHEMBL4617124 | 0.81 | SFRP1 (0.59) | SFRP1WNT3BRD4BRD2BRD3 | |
| SCHEMBL4618174 | 0.80 | SFRP1 (0.55) | SFRP1WNT3BRD4BRD2BRD3 | |
| SCHEMBL4619287 | 0.80 | ALDH1A1 (0.58) | SFRP1WNT3BRD4BRD2BRD3 | |
| SCHEMBL4615963 | 0.79 | ALDH1A1 (0.57) | SFRP1WNT3BRD4BRD2BRD3 | |
| SCHEMBL4618018 | 0.79 | SFRP1 (1.00) | SFRP1WNT3 | |
| SCHEMBL4616993 | 0.79 | SFRP1 (0.62) | SFRP1WNT3BRD4BRD2BRD3 | |
| SCHEMBL4617483 | 0.78 | SFRP1 (0.58) | SFRP1WNT3BRD4BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |