Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 6/20 | 0.33 |
| ▸ | PPARA | Q07869 | 6/20 | 0.33 |
| ▸ | PPARD | Q03181 | 5/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | RORC | P51449 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Morpholine SCHEMBL27733669 | 0.80 | PHGDH (0.33) | PHGDHPPARGPPARAPPARD | |
| SCHEMBL27733824 | 0.76 | TRPV1 (0.37) | PPARGPPARATRPV1RORC | |
| SCHEMBL28775092 | 0.76 | AKR1C3 (0.39) | PHGDHPPARGPPARAPPARD | |
| Morpholine SCHEMBL27733783 | 0.73 | — | — | |
| SCHEMBL27733727 | 0.72 | NOTUM (0.49) | — | |
| SCHEMBL28775101 | 0.72 | PPARG (0.43) | PPARGPPARAPPARD | |
| SCHEMBL27733656 | 0.72 | PPARG (0.36) | PPARGPPARAPPARD | |
| SCHEMBL27713303 | 0.72 | POLB (0.36) | PPARGPPARAPPARDTRPV1 | |
| SCHEMBL27713321 | 0.71 | SCN4A (0.42) | PPARGPPARAPPARD | |
| SCHEMBL27733816 | 0.71 | PPARG (0.39) | PHGDHPPARGPPARAPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |