Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775106 | 0.90 | TRPV1 (0.34) | TRPV1OGAHDAC3HDAC4HDAC1 | |
| SCHEMBL27733800 | 0.88 | FABP4 (0.40) | PTGS1PTGS2FABP4HDAC3HDAC4 | |
| SCHEMBL27733727 | 0.83 | NOTUM (0.49) | — | |
| SCHEMBL28775092 | 0.79 | AKR1C3 (0.39) | PTGS2AKR1C3AKR1C2PPARGPPARA | |
| SCHEMBL28775101 | 0.77 | PPARG (0.43) | OGAAKR1C3AKR1C2PPARGPPARA | |
| SCHEMBL27733849 | 0.77 | PPARG (0.36) | FABP4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL27713303 | 0.77 | POLB (0.36) | TRPV1OGAAKR1C3AKR1C2PPARG | |
| SCHEMBL27733656 | 0.77 | PPARG (0.36) | MAPTAKR1C3AKR1C2PPARGPPARA | |
| SCHEMBL27713321 | 0.77 | SCN4A (0.42) | AKR1C3AKR1C2PPARGPPARA | |
| Morpholine SCHEMBL27733752 | 0.76 | PHGDH (0.34) | TRPV1RORCPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |