Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | PPARD | Q03181 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.34 |
| ▸ | AKR1C3 | P42330 | 4/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.32 |
| ▸ | OGA | O60502 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28775099 | 0.90 | PPARG (0.43) | PPARGPPARAPPARDNPC1RAB9A | |
| SCHEMBL28775091 | 0.88 | PPARG (0.46) | PPARGPPARAPPARDNPC1RAB9A | |
| SCHEMBL27733656 | 0.87 | PPARG (0.36) | PPARGPPARAPPARDNPC1RAB9A | |
| SCHEMBL27713321 | 0.86 | SCN4A (0.42) | PPARGPPARAPPARDNPC1RAB9A | |
| SCHEMBL27713303 | 0.84 | POLB (0.36) | PPARGPPARAPPARDNPC1RAB9A | |
| SCHEMBL27733706 | 0.84 | DYRK1A (0.52) | NPC1RAB9AMEN1POLBKMT2A | |
| SCHEMBL28775092 | 0.79 | AKR1C3 (0.39) | PPARGPPARAPPARDAKR1C3AKR1C2 | |
| SCHEMBL27733824 | 0.77 | TRPV1 (0.37) | PPARGPPARAAKR1C3AKR1C2OGA | |
| SCHEMBL27733702 | 0.77 | PPARG (0.46) | PPARGPPARAPPARDNPC1RAB9A | |
| SCHEMBL27713459 | 0.77 | PPARG (0.36) | PPARGPPARAPPARDRAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101248044-B | Indole compounds | FOURNIER LAB SA | 2012-05-30 | — | — | CN | disclosed |
| CN-101248044-A | Novel indole compounds | FOURNIER LAB SA (FR) | 2008-08-20 | — | — | CN | disclosed |