Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FPR2 | P25090 | 7/20 | 0.41 |
| ▸ | PROKR1 | Q8TCW9 | 7/20 | 0.41 |
| ▸ | ACLY | P53396 | 2/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | NMT1 | P30419 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CCR2 | P41597 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2650212 | 0.98 | L3MBTL1 (0.46) | L3MBTL1MCL1KDM4EPOLBAPEX1 | |
| Hydrochloric Acid SCHEMBL27293487 | 0.96 | L3MBTL1 (0.45) | L3MBTL1MCL1KDM4EPOLBAPEX1 | |
| SCHEMBL6205745 | 0.83 | L3MBTL1 (0.44) | L3MBTL1MCL1KDM4EPOLBAPEX1 | |
| SCHEMBL388129 | 0.80 | L3MBTL1 (0.43) | L3MBTL1MCL1FPR2PROKR1ACLY | |
| SCHEMBL1641772 | 0.80 | L3MBTL1 (0.43) | L3MBTL1MCL1FPR2PROKR1ACLY | |
| SCHEMBL6205744 | 0.78 | L3MBTL1 (0.42) | L3MBTL1MCL1FPR2PROKR1ACLY | |
| SCHEMBL4636620 | 0.78 | MCL1 (0.48) | L3MBTL1MCL1FPR2PROKR1ACLY | |
| SCHEMBL1626536 | 0.78 | L3MBTL1 (0.42) | L3MBTL1MCL1KDM4EFPR2PROKR1 | |
| SCHEMBL3941116 | 0.78 | L3MBTL1 (0.42) | L3MBTL1MCL1FPR2PROKR1ACLY | |
| SCHEMBL15882311 | 0.78 | ACLY (0.50) | L3MBTL1MCL1FPR2PROKR1ACLY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208299-A | Diarylsulfone sulfonamides and use therof | WYETH CORP (US) | 2008-06-25 | — | — | CN | disclosed |