Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27713382 | 0.87 | FFAR1 (0.36) | POLBKDM4EALDH1A1L3MBTL1GAA | |
| SCHEMBL27733810 | 0.83 | POLB (0.33) | POLBKDM4EPKMALDH1A1ESR1 | |
| SCHEMBL4501360 | 0.67 | MAOA (0.35) | ALDH1A1GAAHPGDMTNR1A | |
| SCHEMBL27606816 | 0.65 | RAB9A (0.36) | POLBKDM4ETP53TDP1L3MBTL1 | |
| SCHEMBL27446644 | 0.64 | — | — | |
| SCHEMBL27475943 | 0.64 | — | — | |
| SCHEMBL28805616 | 0.64 | — | — | |
| SCHEMBL27794981 | 0.64 | CYP26B1 (0.33) | — | |
| SCHEMBL4606288 | 0.63 | MAOA (0.33) | ALDH1A1GAAHPGD | |
| SCHEMBL28069778 | 0.63 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101208335-A | Pyrazole derivatives, their manufacture and their use as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2008-06-25 | — | — | CN | disclosed |