Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.50 |
| ▸ | GHSR | Q92847 | 2/20 | 0.50 |
| ▸ | HTR6 | P50406 | 2/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.49 |
| ▸ | ALPI | P09923 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | XIAP | P98170 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27734638 | 1.00 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL19234913 | 0.89 | HDAC1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL20715878 | 0.89 | HDAC1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5078465 | 0.89 | HDAC1 (0.62) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5607923 | 0.88 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL31702460 | 0.88 | CES1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL5608211 | 0.88 | CES1 (0.58) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL31689455 | 0.88 | POLB (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL14422985 | 0.88 | ALDH1A1 (0.66) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA | |
| SCHEMBL19234908 | 0.88 | POLB (0.57) | ALDH1A1SMN1; SMN2MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101400699-A | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | CN | claimed |
| CN-101400699-A | Human glucagon-like-peptide-1 modulators and their use in the treatment of diabetes and related conditions | BRISTOL MYERS SQUIBB CO (US) | 2009-04-01 | — | — | CN | disclosed |