Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | GHSR | Q92847 | 1/20 | 0.55 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.53 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.53 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5607923 | 1.00 | ALDH1A1 (0.66) | ALDH1A1HPGDMAPTLMNAMEN1 | |
| SCHEMBL31689516 | 0.88 | ALDH1A1 (0.51) | ALDH1A1HPGDMAPTLMNAMEN1 | |
| SCHEMBL27734636 | 0.88 | ALDH1A1 (0.55) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL27734638 | 0.88 | ALDH1A1 (0.55) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL5078465 | 0.88 | HDAC1 (0.62) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL20715878 | 0.88 | HDAC1 (0.62) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL19234913 | 0.88 | HDAC1 (0.62) | ALDH1A1HPGDLMNAMEN1KMT2A | |
| SCHEMBL4935236 | 0.87 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPTLMNAMEN1 | |
| SCHEMBL4935233 | 0.87 | ALDH1A1 (0.60) | ALDH1A1HPGDMAPTLMNAMEN1 | |
| SCHEMBL19234892 | 0.87 | POLB (0.57) | ALDH1A1HPGDLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7262269-B2 | Method for screening combinational bead library; ligands for cancer cells | THE REGENTS OF UNIVERSITY OF CALIFORNIA (US) | 2007-08-28 | — | — | US | disclosed |
| US-7262269-B2 | Method for screening combinational bead library; ligands for cancer cells | THE REGENTS OF UNIVERSITY OF CALIFORNIA (US) | 2007-08-28 | — | — | US | disclosed |