Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3582413 | 0.81 | L3MBTL1 (0.55) | L3MBTL1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL27978837 | 0.80 | ATM (0.50) | L3MBTL1SMN1; SMN2ALDH1A1HTTGAA | |
| SCHEMBL3163805 | 0.80 | LMNA (0.53) | L3MBTL1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL1081817 | 0.79 | L3MBTL1 (0.53) | L3MBTL1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL12549368 | 0.79 | L3MBTL1 (0.53) | L3MBTL1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL6050178 | 0.78 | L3MBTL1 (0.48) | L3MBTL1SMN1; SMN2ALDH1A1HTTGAA | |
| SCHEMBL27755282 | 0.78 | L3MBTL1 (0.52) | L3MBTL1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL3170098 | 0.77 | GLA (0.58) | L3MBTL1TSHRPOLBLMNAGLA | |
| SCHEMBL3988863 | 0.76 | L3MBTL1 (0.50) | L3MBTL1TSHRALOX15HSD17B10SMN1; SMN2 | |
| SCHEMBL19621307 | 0.76 | L3MBTL1 (0.46) | L3MBTL1TSHRALOX15HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101389331-A | Amino acid derivatives of indolinone based protein kinase inhibitors | SCRIPPS RESEARCH INST (US) | 2009-03-18 | — | — | CN | disclosed |