SCHEMBL27734830

SCHEMBL27734830

OC1c2ccccc2C=CC1(c1ccccc1)c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.34
CYP2D6 P10635 1/20 0.33
HSD11B1 P28845 1/20 0.31
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28116554 0.74 HTR2A (0.35) HTR2ACYP2D6ATM
SCHEMBL9233000 0.73 BRD4 (0.35) HTR2ACYP2D6ATM
SCHEMBL995535 0.72 HTR2A (0.37) HTR2ACYP2D6
SCHEMBL4784825 0.70 CYP2D6 (0.35) HTR2ACYP2D6ATM
Methane SCHEMBL5718665 0.69 HTR2A (0.35) HTR2ACYP2D6
SCHEMBL15212735 0.69 RET (0.33) HTR2ACYP2D6
SCHEMBL6763812 0.67 HTR2A (0.33) HTR2ACYP2D6ATM
SCHEMBL29061664 0.67 HTR2A (0.32) HTR2A
SCHEMBL9373705 0.67 BRD4 (0.33) HTR2ACYP2D6
SCHEMBL9493813 0.66 CYP2D6 (0.32) CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101251656-A Antidazzle laminate, coated antidazzle laminate, antidazzle material and manufacturing method of antidazzle material MGC FILSHEET CO LTD (JP) 2008-08-27 CN disclosed