Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.37 |
| ▸ | KDM1A | O60341 | 4/20 | 0.33 |
| ▸ | MAOA | P21397 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 4/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CCL2 | P13500 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28116554 | 0.81 | HTR2A (0.35) | HTR2ACYP2D6KDM4EBRD4CCL2 | |
| SCHEMBL9233000 | 0.79 | BRD4 (0.35) | HTR2ACYP2D6KDM4EBRD4CCL2 | |
| SCHEMBL10445171 | 0.79 | HTR2A (0.38) | HTR2AKDM1AMAOAMAOBCYP2D6 | |
| Methane SCHEMBL5718665 | 0.79 | HTR2A (0.35) | HTR2ACYP2D6KDM4ELMNATP53 | |
| SCHEMBL15212735 | 0.75 | RET (0.33) | HTR2ACYP2D6CHRM2CHRM3RET | |
| SCHEMBL28633554 | 0.75 | SIGMAR1 (0.39) | HTR2AKDM1ACYP2D6KDM4ELMNA | |
| SCHEMBL8075462 | 0.75 | HTR2A (0.33) | HTR2ABRD4CCL2 | |
| SCHEMBL6763812 | 0.73 | HTR2A (0.33) | HTR2ACYP2D6KDM4ESMN1; SMN2 | |
| SCHEMBL27734830 | 0.72 | HTR2A (0.34) | HTR2ACYP2D6 | |
| SCHEMBL28725904 | 0.69 | BRD4 (0.36) | HTR2ACYP2D6KDM4EBRD4CCL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2456306-A1 | VITAMIN C AND VITAMIN K, AND COMPOSITIONS THEREOF FOR TREATMENT OF OSTEOLYSIS OR PROLONGATION OF PROSTHETIC IMPLANT | Summa Health System (US) | 2012-05-30 | — | — | EP | disclosed |
| WO-2011011317-A1 | VITAMIN C AND VITAMIN K, AND COMPOSITIONS THEREOF FOR TREATMENT OF OSTEOLYSIS OR PROLONGATION OF PROSTHETIC IMPLANT | SUMMA HEALTH SYSTEM (US) | 2011-01-27 | — | — | WO | disclosed |