Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CCL2 | P13500 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28725904 | 0.82 | BRD4 (0.36) | BRD4CCL2SIGMAR1HTR2ACHRNA7 | |
| SCHEMBL28116554 | 0.82 | HTR2A (0.35) | BRD4CCL2HTR2ACYP2D6KDM4E | |
| SCHEMBL995535 | 0.79 | HTR2A (0.37) | BRD4CCL2HTR2ACYP2D6KDM4E | |
| SCHEMBL6604680 | 0.79 | BRD4 (0.35) | BRD4CCL2SIGMAR1HTR2ACHRNA7 | |
| SCHEMBL15212735 | 0.77 | RET (0.33) | HTR2ACYP2D6CHRM2CHRM3RET | |
| Methane SCHEMBL5718665 | 0.77 | HTR2A (0.35) | SIGMAR1HTR2ACYP2D6KDM4ELMNA | |
| SCHEMBL9373705 | 0.74 | BRD4 (0.33) | BRD4CCL2SIGMAR1HTR2ACYP2D6 | |
| SCHEMBL4784825 | 0.74 | CYP2D6 (0.35) | BRD4CCL2HTR2ACYP2D6KDM4E | |
| SCHEMBL27734830 | 0.73 | HTR2A (0.34) | HTR2ACYP2D6ATM | |
| SCHEMBL27942046 | 0.72 | ALDH1A1 (0.36) | BRD4CCL2SIGMAR1HTR2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3265447-B1 | BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION | HUNTSMAN ADVANCED MAT AMERICAS LLC (US) | 2023-03-01 | — | — | EP | disclosed |
| CN-107428709-B | Cationic direct dyes | 巴斯夫欧洲公司 | 2021-10-08 | — | — | CN | disclosed |
| US-20180030264-A1 | Benzoxazine Low Temperature Curable Composition | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC | 2018-02-01 | — | — | US | disclosed |
| EP-3265447-A1 | BENZOXAZINE LOW TEMPERATURE CURABLE COMPOSITION | Huntsman Advanced Materials Americas LLC (US) | 2018-01-10 | — | — | EP | disclosed |
| EP-0661322-A2 | Modified polyepoxy compound, process for producing the compound, and epoxy resin composition | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1995-07-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180030264-A1 | Benzoxazine Low Temperature Curable Composition | CRYZ, PIEZO1, PSMD12 | BRD4 813/4885CCL2 4778/4885SIGMAR1 162/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.