Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.30 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27755569 | 0.89 | PRKCZ (0.36) | PRKCZ | |
| SCHEMBL27735037 | 0.87 | PRKCZ (0.35) | PRKCZ | |
| SCHEMBL27755571 | 0.85 | GRM5 (0.33) | PRKCZ | |
| SCHEMBL27755562 | 0.85 | FLT3 (0.34) | MEN1KMT2APRKCZ | |
| SCHEMBL27755568 | 0.85 | GRM5 (0.34) | MEN1KMT2APRKCZ | |
| SCHEMBL27735008 | 0.85 | CYP2A6 (0.34) | PRKCZ | |
| SCHEMBL27755589 | 0.84 | PRKCZ (0.31) | PRKCZ | |
| SCHEMBL27735000 | 0.83 | PRKCZ (0.34) | PRKCZ | |
| SCHEMBL27735007 | 0.83 | SMN1; SMN2 (0.36) | PRKCZ | |
| SCHEMBL27598051 | 0.81 | NPSR1 (0.40) | MEN1KMT2APRKCZ |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101486683-B | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | Sanitary Material R&D Management Co.,Ltd. (JP) | 2011-12-21 | — | — | CN | disclosed |
| CN-101486683-A | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI R&D MAN CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |
| CN-100473647-C | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI CO LTD (JP) | 2009-04-01 | — | — | CN | disclosed |