Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | BRAF | P15056 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27755569 | 0.91 | PRKCZ (0.36) | PRKCZMAPT | |
| SCHEMBL27735006 | 0.88 | CYP2A6 (0.39) | CYP2A6PRKCZMAPTMAPK1HTT | |
| SCHEMBL27735000 | 0.87 | PRKCZ (0.34) | PRKCZ | |
| SCHEMBL27755573 | 0.87 | GRM5 (0.33) | CYP2A6PRKCZBRAF | |
| SCHEMBL27755562 | 0.85 | FLT3 (0.34) | PRKCZMAPTMAPK1HTTNPC1 | |
| SCHEMBL27735005 | 0.85 | MEN1 (0.34) | PRKCZ | |
| SCHEMBL27735007 | 0.85 | SMN1; SMN2 (0.36) | PRKCZMAPT | |
| SCHEMBL27755589 | 0.83 | PRKCZ (0.31) | PRKCZ | |
| SCHEMBL27598051 | 0.83 | NPSR1 (0.40) | PRKCZMAPTNPC1RAB9A | |
| SCHEMBL27735037 | 0.83 | PRKCZ (0.35) | PRKCZHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101486683-B | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | Sanitary Material R&D Management Co.,Ltd. (JP) | 2011-12-21 | — | — | CN | disclosed |
| CN-101486683-A | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI R&D MAN CO LTD (JP) | 2009-07-22 | — | — | CN | disclosed |
| CN-100473647-C | Pyridazinone and triazinone compounds and their use as pharmaceutical formulations | EISAI CO LTD (JP) | 2009-04-01 | — | — | CN | disclosed |