Demannose

Demannose

SCHEMBL27735211

O=CC(O)C(O)C(O)C(O)CO.Oc1ccccc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.38
LMNA P02545 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
GLA P06280 1/20 0.38
CA3 P07451 1/20 0.38
CA4 P22748 1/20 0.38
CA9 Q16790 1/20 0.38
CA14 Q9ULX7 1/20 0.38
PDE4A P27815 1/20 0.37
USP2 O75604 1/20 0.35
SLCO1B1 Q9Y6L6 1/20 0.35
MAPT P10636 2/20 0.33
KDM4E B2RXH2 1/20 0.31
GAA P10253 1/20 0.31
FNTA P49354 1/20 0.31
FNTB P49356 1/20 0.31
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demannose SCHEMBL3515070 1.00 TDP1 (0.38) TDP1LMNAL3MBTL1CA12CA1
Demannose SCHEMBL10808821 0.97 TDP1 (0.35) TDP1LMNAL3MBTL1CA12CA1
Xylose SCHEMBL28295161 0.95 TDP1 (0.39) TDP1LMNAL3MBTL1CA12CA1
Demannose SCHEMBL28270412 0.94 TDP1 (0.33) TDP1LMNAL3MBTL1CA12CA1
Demannose SCHEMBL11581936 0.94 USP2 (0.39) TDP1LMNAL3MBTL1CA12CA1
Demannose SCHEMBL1996276 0.91 LMNA (0.42) TDP1LMNAL3MBTL1PDE4AUSP2
Demannose SCHEMBL28138394 0.91 LMNA (0.42) TDP1LMNAL3MBTL1PDE4AUSP2
Galactose SCHEMBL16210938 0.91 LMNA (0.42) TDP1LMNAL3MBTL1PDE4AUSP2
Demannose SCHEMBL27695581 0.88 LMNA (0.40) TDP1LMNAL3MBTL1CA12CA1
Demannose SCHEMBL27784462 0.87 LMNA (0.50) TDP1LMNAL3MBTL1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024151554-A2 COMBINATION OF NON-VIABLE CELLS OF STREPTOCOCCUS PYOGENES AND IMMUNE CHECKPOINT INHIBITOR FOR THE TREATMENT OF TRIPLE NEGATIVE BREAST CANCER AND NON-MUSCLE INVASIVE BLADDER CANCER PROTARA THERAPEUTICS, INC. (US) 2024-07-18 WO disclosed
CN-107995919-B Proteins for removal of sulfur-containing and/or acidic compounds in downhole fluids 通用电气(GE)贝克休斯有限责任公司 2021-03-02 CN disclosed
CN-111729053-A Traditional Chinese medicine composition for soothing liver and harmonizing stomach, Weitean pill and preparation method 张家口义王堂生物科技有限责任公司 2020-10-02 CN disclosed
CN-108913400-A A kind of low-residual detergent 李绍文 2018-11-30 CN disclosed
CN-108778288-A It can be used for treating antagonist derived from the mannose of the FimH of disease 菲姆布里昂医疗公司 2018-11-09 CN disclosed
CN-108096123-A A kind of compound plant goes acne stoste and preparation method thereof 广州重生化妆品实业有限公司 2018-06-01 CN disclosed
CN-104263569-B A kind of centipedaplant herb anti-inflammatory perfumed soap and preparation method thereof 淄博职业学院 2017-10-20 CN disclosed
CN-101400788-B Compositions and methods for treating collagen-mediated diseases 奥克思利尤姆国际控股公司 2016-06-29 CN disclosed
CN-104263569-A Anti-inflammatory homalocladium platycladium soap and preparation method thereof LI ZHENGMEI 2015-01-07 CN disclosed
CN-103764141-A Site-activated binding systems that selectively enhance the biological activity of phenolic compounds at target sites LIVELEAF INC 2014-04-30 CN disclosed
CN-102406666-B Preparation method for gallnut sustained release gel ZHANG SHUANG 2013-02-13 CN disclosed
CN-101897714-B Use of paeoniflorin BEIJING ZHUOYUE TONGCHUANG PHARMACEUTICAL RES INST 2012-11-28 CN disclosed
CN-101249189-B Quality control method of muskiness bone-knitting capsules WENLONG YANG 2012-06-27 CN disclosed
CN-102406666-A Preparation method for gallnut sustained release gel SHUANG ZHANG 2012-04-11 CN disclosed
CN-101904948-B Traditional Chinese medicine preparation of Xinzhongsheng pills and preparation method thereof GUANGDONG ZHONGSHENG PHARMACEUTICAL CO LTD 2011-09-28 CN disclosed
CN-101904948-A Traditional Chinese medicine preparation of Xinzhongsheng pills and preparation method thereof GUANGDONG ZHONGSHENG PHARMACEUTICAL CO LTD 2010-12-08 CN disclosed
CN-101897714-A Use of paeoniflorin BEIJING ZHUOYUE TONGCHUANG PHARMACEUTICAL RES INST 2010-12-01 CN disclosed
CN-101400788-A Compositions and methods for treating collagen-mediated diseases AUXILIUM INT HOLDINGS INC (US) 2009-04-01 CN disclosed
CN-101249189-A Quality control method of muskiness bone-knitting capsules WENLONG YANG (CN) 2008-08-27 CN disclosed