Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | NPC1 | O15118 | 4/20 | 0.64 |
| ▸ | RAB9A | P51151 | 4/20 | 0.64 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.54 |
| ▸ | APP | P05067 | 3/20 | 0.49 |
| ▸ | CRHBP | P24387 | 2/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | F3 | P13726 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2028301 | 0.83 | APP (0.65) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL10621315 | 0.82 | MAPT (0.93) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL3738691 | 0.82 | MAPT (0.93) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL10021997 | 0.82 | MAPT (0.93) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL4576499 | 0.79 | MAPT (1.00) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL3742453 | 0.79 | MAPT (1.00) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL5171393 | 0.78 | MAPT (0.68) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL2025945 | 0.78 | ALDH1A1 (0.51) | MAPTHPGDALDH1A1KMT2AMEN1 | |
| SCHEMBL812295 | 0.75 | ALDH1A1 (1.00) | MAPTNPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL1524525 | 0.75 | ALDH1A1 (1.00) | MAPTNPC1RAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101394830-A | Cosmetic agents comprising purine and/or purine derivatives I | HENKEL KGAA (DE) | 2009-03-25 | — | — | CN | disclosed |