Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.59 |
| ▸ | CRHBP | P24387 | 3/20 | 0.59 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.59 |
| ▸ | METAP1 | P53582 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | PIM1 | P11309 | 1/20 | 0.51 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.51 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.49 |
| ▸ | SNCA | P37840 | 3/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735454 | 0.83 | MAPT (0.64) | APPALDH1A1CRHBPCRHR2METAP1 | |
| SCHEMBL2024634 | 0.79 | ALDH1A1 (0.51) | APPALDH1A1METAP1KMT2AHPGD | |
| SCHEMBL5171393 | 0.79 | MAPT (0.68) | APPALDH1A1CRHBPCRHR2METAP1 | |
| SCHEMBL2025945 | 0.79 | ALDH1A1 (0.51) | APPALDH1A1KMT2AHPGDMEN1 | |
| SCHEMBL29711922 | 0.75 | METAP1 (0.86) | APPALDH1A1CRHBPCRHR2METAP1 | |
| SCHEMBL9196949 | 0.75 | ALDH1A1 (1.00) | APPALDH1A1CRHBPCRHR2METAP1 | |
| SCHEMBL4096609 | 0.72 | METAP1 (1.00) | APPALDH1A1CRHBPCRHR2METAP1 | |
| SCHEMBL7005334 | 0.72 | ALDH1A1 (0.58) | APPALDH1A1CRHBPCRHR2METAP1 | |
| SCHEMBL12865918 | 0.71 | ALDH1A1 (0.91) | APPALDH1A1CRHBPCRHR2METAP1 | |
| SCHEMBL4037782 | 0.70 | METAP1 (0.76) | APPALDH1A1CRHBPCRHR2METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778176-B1 | COMPOSITION FOR COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2012-07-25 | — | — | EP | claimed |
| US-7413579-B2 | Method for dyeing fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2008-08-19 | — | — | US | claimed |
| US-7300472-B2 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-11-27 | — | — | US | claimed |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2007-01-04 | — | — | US | claimed |
| EP-1534227-B1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KGAA (DE) | 2006-12-27 | — | — | EP | claimed |
| US-20060265818-A1 | At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections | HENKEL KOMMANDITGESELLSCHAFT AUF AKLLEN (HENKEL KGAA) (DE) | 2006-11-30 | — | — | US | claimed |
| EP-1433469-B1 | Composition for dyeing keratinous fibres | HENKEL KGAA (DE) | 2006-10-11 | — | — | EP | claimed |
| US-7105032-B2 | Agents used for dyeing keratinous fibers | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) | 2006-09-12 | — | — | US | claimed |
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | HENKEL AG & CO. KGAA (DE) | 2005-07-07 | — | — | US | claimed |
| EP-1433469-A1 | Composition for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | claimed |
| EP-1730049-B1 | COSMETIC PORTION | HENKEL AG & CO KGAA (DE) | 2018-09-12 | — | — | EP | disclosed |
| EP-1900393-B1 | Hydrogen peroxide activation with diones and imidazoles | HENKEL AG & CO KGAA (DE) | 2018-02-28 | — | — | EP | disclosed |
| EP-1978840-B1 | AUXILIARY AGENT FOR STYLISHLY COLOURING KERATIN-CONTAINING FIBRES | HENKEL AG & CO KGAA (DE) | 2016-07-06 | — | — | EP | disclosed |
| EP-2026754-B1 | LIGHTENING AND/OR COLOURING AGENT COMPRISING CYCLIC UREA DERIVATIVES | HENKEL AG & CO KGAA (DE) | 2015-09-30 | — | — | EP | disclosed |
| EP-1871486-B1 | OXIDATION DYES COMPRISING PERSULFATES AND/OR PEROXODISULFATES | HENKEL AG & CO KGAA (DE) | 2014-07-09 | — | — | EP | disclosed |
| EP-1433469-A1 | Composition for dyeing keratinous fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-30 | — | — | EP | disclosed |
| EP-1430874-A2 | 4-N, N-Bis-(monohydroxyalkyl)amino-3-nitrophenol derivatives in dyeing compositions for keratinic fibres | Henkel Kommanditgesellschaft auf Aktien (DE) | 2004-06-23 | — | — | EP | disclosed |
| WO-2004031164-A1 | HAIR DYES COMPRISING M-PHENYLENEDIAMINE DERIVATIVES AS COUPLING COMPONENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-04-15 | — | — | WO | disclosed |
| WO-2004022016-A1 | AGENTS USED FOR DYEING KERATINOUS FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2004-03-18 | — | — | WO | disclosed |
| WO-2003030845-A1 | AGENT FOR THE COLORATION OF KERATIN-CONTAINING FIBERS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2003-04-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050144740-A1 | Agents used for dyeing keratinous fibers | KRT18, TUBB3, DSG1 | APP 2519/4885ALDH1A1 343/4885CRHBP 2752/4885 |
| US-20060265818-A1 | At least two oxidation dye precursors, at least one of which must be of the developer type or at least two oxo dye precursors, at least one of which must be a reactive carbonyl compound; hair dyes producing uniform and natural-looking, lightened color reflections | KRT18, CUTA, PLOD2 | APP 959/4885ALDH1A1 159/4885CRHBP 3139/4885 |
| US-20070000074-A1 | Agents for coloring fibers containing keratin | KRT18, COL1A1, CYC1 | APP 2312/4885ALDH1A1 780/4885CRHBP 1735/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.