Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 3/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.33 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | FSHR | P23945 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27756131 | 0.85 | NR3C2 (0.36) | NR3C2HSD11B1TNKSTNKS2ALDH1A1 | |
| SCHEMBL27756109 | 0.80 | TNKS (0.34) | TNKSTNKS2FSHRALDH1A1LMNA | |
| SCHEMBL27735512 | 0.80 | NR3C2 (0.33) | NR3C2HSD11B1LMNAMAPTGFER | |
| SCHEMBL27862262 | 0.77 | NR3C2 (0.33) | NR3C2 | |
| SCHEMBL755966 | 0.76 | TNKS (0.45) | HSD11B1TNKSTNKS2 | |
| SCHEMBL27735494 | 0.73 | HSD11B1 (0.34) | HSD11B1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL756162 | 0.73 | NR3C2 (0.46) | NR3C2HSD11B1FSHRALDH1A1LMNA | |
| SCHEMBL27735504 | 0.71 | HSD11B1 (0.34) | HSD11B1ALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL27756113 | 0.71 | ALDH1A1 (0.32) | ALDH1A1MAPT | |
| SCHEMBL27735495 | 0.67 | HSD11B1 (0.33) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101379048-B | Benzoxazines and related nitrogen-containing heterobicyclic compounds useful as mineralocorticoid receptor modulating agents | MITSUBISHI TANABE PHARMA CORP | 2012-03-21 | — | — | CN | disclosed |
| CN-101379048-A | Benzo oxazines and related nitrogen-containing heterobicyclic compounds useful as mineralocorticoid receptor modulating agents | MITSUBISHI TANABE PHARMA CORP (JP) | 2009-03-04 | — | — | CN | disclosed |