Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.62 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.62 |
| ▸ | RELA | Q04206 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.40 |
| ▸ | TUBB | P07437 | 3/20 | 0.40 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.40 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.40 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.40 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.40 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27735776 | 0.92 | NFKB1 (0.70) | NFKB1NFKB2RELAALDH1A1ABL1 | |
| SCHEMBL2141311 | 0.90 | NFKB1 (0.57) | NFKB1NFKB2RELAALDH1A1ABL1 | |
| SCHEMBL2141238 | 0.89 | NFKB1 (0.60) | NFKB1NFKB2RELAALDH1A1ABL1 | |
| SCHEMBL2139185 | 0.83 | NFKB1 (0.66) | NFKB1NFKB2RELAALDH1A1ABL1 | |
| SCHEMBL2139575 | 0.82 | NFKB1 (0.87) | NFKB1NFKB2RELAALDH1A1ABL1 | |
| SCHEMBL2139370 | 0.76 | NFKB1 (1.00) | NFKB1NFKB2RELAALDH1A1ABL1 | |
| SCHEMBL30316128 | 0.76 | NFKB1 (1.00) | NFKB1NFKB2RELAALDH1A1ABL1 | |
| SCHEMBL14046922 | 0.75 | NFKB1 (0.71) | NFKB1NFKB2RELAALDH1A1ABL1 | |
| SCHEMBL2140541 | 0.75 | NFKB1 (0.61) | NFKB1NFKB2RELAALDH1A1ABL1 | |
| SCHEMBL2139666 | 0.74 | NFKB1 (0.69) | NFKB1NFKB2RELAALDH1A1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101405278-A | Novel heterocyclic NF-kB inhibitors | 4SC AG (DE) | 2009-04-08 | — | — | CN | disclosed |