Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GPR3 | P46089 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824520 | 1.00 | KDM4E (0.42) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL223540 | 0.79 | CYP1A2 (0.43) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL7548858 | 0.79 | KDM4E (0.42) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL1996212 | 0.79 | ALDH1A1 (0.43) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL6005051 | 0.79 | KDM4E (0.42) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL29947454 | 0.79 | ALDH1A1 (0.43) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL32679237 | 0.75 | GRM5 (0.45) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL32679238 | 0.75 | GRM5 (0.45) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL32679239 | 0.75 | GRM5 (0.45) | KDM4EGPR3EGFRCYP1A2ALDH1A1 | |
| SCHEMBL10669046 | 0.71 | KDM4E (0.46) | KDM4EGPR3EGFRCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-11080131-A | — | — | None | — | — | JP | disclosed |
| US-7777218-B1 | Memory cell containing copolymer containing diarylacetylene portion | SPANSION LLC (US) | 2010-08-17 | — | — | US | disclosed |
| US-7105374-B1 | Memory cell containing copolymer containing diarylacetylene portion | SPANSION LLC (US) | 2006-09-12 | — | — | US | disclosed |
| JP-H1180131-A | ETHYNYLPYRIMIDINE DERIVATIVE | MITSUBISHI CHEM CORP | 1999-03-26 | — | — | JP | disclosed |